BME 412 Tissue Engineering
BME 412. Tissue Engineering (3) This course will cover: (a) the fundamentals and tools which are fundamentals of polymer scaffolds and their use in artificial tissues; Regulation of cell responses in the rational design and development of engineered replacement tissue; Understanding the biological, chemical and mechanical components of intra and intercellular communication; Preliminary discussions on real-life clinical experiences. (b) Biomed and Biotechnological Applications which will cover the applications of tissue engineering and builds upon the prior course fundamentals and tools. Emphasis is placed on applying the fundamental principles and concepts to problems in clinical medicine and large scale industrial manufacturing. Topics include: skin replacement, cartilage tissue repair, bone tissue engineering, nerve regeneration, corneal and retinal transplants, ligaments and tendons, blood substitutes, artificial pancreas, artificial liver, tissue integration with prosthetics, vascular grafts, cell encapsulation and angiogenesis. Prerequisites: BME 128, BME 410 or consent of instructor.